China Geological Environmental Monitoring InstituteHost
Advanced Search
Previous Article Next Article
2024 Vol. 51, No. 2
Article Contents
Article navigation > Hydrogeology & Engineering Geology > 2024 > 51(2): 13-22
Next Article Previous Article

WANG Jialin, PAN Jinwei, LIU Fei. Study on the characteristics and mechanism of antibiotic pollution in different aquifers[J]. Hydrogeology & Engineering Geology, 2024, 51(2): 13-22. doi: 10.16030/j.cnki.issn.1000-3665.202311008
Citation: WANG Jialin, PAN Jinwei, LIU Fei. Study on the characteristics and mechanism of antibiotic pollution in different aquifers[J]. Hydrogeology & Engineering Geology, 2024, 51(2): 13-22. doi: 10.16030/j.cnki.issn.1000-3665.202311008
shu

Study on the characteristics and mechanism of antibiotic pollution in different aquifers

  • 1.

    Key Laboratory of Groundwater Conservation of Ministry of Water Resources （in Preparation）, China University of Geosciences （Beijing）, Beijing　100083, China

More Information
Received Date:  05 November 2023
Revised Date:  05 February 2024
Publish Date:  15 March 2024
    Abstract

  • The risk posed by antibiotics in various aquifers has attracted wide attention. This study investigated the pollution characteristics and controlling factors of antibiotics in different types of aquifers, and identified the indicator factors of antibiotic pollution in aquifers based on a total of 309 sets of samples from Songnen Plain, North China Plain, and Southwest Karst area. The concentrations of 35 antibiotics were analyzed using ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The results show that: (1) all 35 antibiotics were detected, with karst aquifers (34 types) and North China porous aquifers (32 types) mainly containing quinolones and macrolide antibiotics, while only 6 types of antibiotics, mainly erythromycin, were detected in Northeast porous aquifers. In porous aquifers, the overall pollution in Northeast China is characterized by low concentrations (median = 2.07 ng/L, detection rate = 100%), while the pollution in North China is relatively heavy (11.76 ng/L), accounting for 49% of the spatial distribution. In the karst aquifers, the antibiotic pollution is characterized by high concentrations (37.5 ng/L) and a large spatial extent (87%). (2) The characteristic differences in antibiotic pollution between karst and porous aquifers are attributed to the hydrogeological conditions (openness and permeability), while the emission intensity of antibiotics is the primary reason for the differences between porous aquifers in different regions. (3) Cluster analysis based on correlation coefficients identified the indicator factors of antibiotics in different types of aquifers. Total organic carbon (TOC) can effectively indicate the antibiotic pollution in porous aquifers, while ${\mathrm{NH}}_4^+ $ and ${\mathrm{SO}}_4^{2-} $ reveal a positive correlation between human activities and antibiotics. Groundwater property parameters are reliable indicators of antibiotic pollution in karst aquifers, with lower antibiotic concentrations observed in alkaline and oxidizing karst water. The research results can provide scientific basis for regional prevention and control of emerging organic contaminants in groundwater.

    • FullText(HTML)
  • 加载中
    • References
  • [1] WANG Kelin,ZHANG Chunhua,CHEN Hongsong,et al. Karst landscapes of China:Patterns,ecosystem processes and services[J]. Landscape Ecology,2019,34(12):2743 − 2763. doi: 10.1007/s10980-019-00912-w

    CrossRef Google Scholar

    [2] LI Sinan,ZHAO Xiaoqing,PU Junwei,et al. Optimize and control territorial spatial functional areas to improve the ecological stability and total environment in Karst areas of Southwest China[J]. Land Use Policy,2021,100:104940. doi: 10.1016/j.landusepol.2020.104940

    CrossRef Google Scholar

    [3] HE Keqiang,JIA Yuyue,WANG Fei,et al. Overview of karst geo-environments and karst water resources in north and south China[J]. Environmental Earth Sciences,2011,64(7):1865 − 1873. doi: 10.1007/s12665-011-0998-8

    CrossRef Google Scholar

    [4] KALHOR K,GHASEMIZADEH R,RAJIC L,et al. Assessment of groundwater quality and remediation in Karst aquifers:A review[J]. Groundwater for Sustainable Development,2019,8:104 − 121. doi: 10.1016/j.gsd.2018.10.004

    CrossRef Google Scholar

    [5] XIANG Shizheng,WANG Xusheng,MA Wen,et al. Response of microbial communities of Karst river water to antibiotics and microbial source tracking for antibiotics[J]. Science of the Total Environment,2020,706:135730. doi: 10.1016/j.scitotenv.2019.135730

    CrossRef Google Scholar

    [6] FORD D,WILLIAMS P. Introduction to Karst[M]. New Zealand:Karst Hydrogeology and Geomorphology,2007:1 − 8.

    Google Scholar

    [7] WEARY D,DOCTOR D,WEARY D J,et al. Karst in the United States:A digital map compilation and database[J]. Center for Integrated Data Analytics Wisconsin Science Center,2014.

    Google Scholar

    [8] WHITE W B,CULVER D C,HERMAN J S,et al. Karst lands[J]. American Scientist,1995,83(5):450 − 459.

    Google Scholar

    [9] HUANG Fuyang,ZOU Shengzhang,DENG Dongdong,et al. Antibiotics in a typical Karst river system in China:Spatiotemporal variation and environmental risks[J]. Science of the Total Environment,2019,650:1348 − 1355. doi: 10.1016/j.scitotenv.2018.09.131

    CrossRef Google Scholar

    [10] ZOU Shengzhang,HUANG Fuyang,CHEN Liang,et al. The occurrence and distribution of antibiotics in the Karst river system in Kaiyang,Southwest China[J]. Water Science & Technology(Water Supply),2018,18(5/6):2044 − 2052.

    Google Scholar

    [11] LAPWORTH D J,BARAN N,STUART M E,et al. Emerging organic contaminants in groundwater:A review of sources,fate and occurrence[J]. Environmental Pollution,2012,163:287 − 303. doi: 10.1016/j.envpol.2011.12.034

    CrossRef Google Scholar

    [12] LUKAČ REBERSKI J,TERZIĆ J,MAURICE L D,et al. Emerging organic contaminants in Karst groundwater:A global level assessment[J]. Journal of Hydrology,2022,604:127242. doi: 10.1016/j.jhydrol.2021.127242

    CrossRef Google Scholar

    [13] BEN Weiwei,PAN Xun,QIANG Zhimin. Occurrence and partition of antibiotics in the liquid and solid phases of swine wastewater from concentrated animal feeding operations in Shandong Province,China[J]. Environmental Science-Processes & Impacts,2013,15(4):870 − 875.

    Google Scholar

    [14] CHEN Yongshan,ZHANG Haibo,LUO Yongming,et al. Occurrence and dissipation of veterinary antibiotics in two typical swine wastewater treatment systems in east China[J]. Environmental Monitoring and Assessment,2012,184(4):2205 − 2217. doi: 10.1007/s10661-011-2110-y

    CrossRef Google Scholar

    [15] JIANG Hongyou,ZHANG Dandan,XIAO Shichang,et al. Occurrence and sources of antibiotics and their metabolites in river water,WWTPs,and swine wastewater in Jiulongjiang River basin,south China[J]. Environmental Science and Pollution Research,2013,20(12):9075 − 9083. doi: 10.1007/s11356-013-1924-2

    CrossRef Google Scholar

    [16] LI Cheng,CHEN Jiayi,WANG Jihua,et al. Occurrence of antibiotics in soils and manures from greenhouse vegetable production bases of Beijing,China and an associated risk assessment[J]. Science of the Total Environment,2015,521:101 − 107.

    Google Scholar

    [17] WANG Yuwen,LI Yan,HU Anyi,et al. Monitoring,mass balance and fate of pharmaceuticals and personal care products in seven wastewater treatment plants in Xiamen City,China[J]. Journal of Hazardous Materials,2018,354:81 − 90. doi: 10.1016/j.jhazmat.2018.04.064

    CrossRef Google Scholar

    [18] WEI Ruicheng,GE Feng,HUANG Siyu,et al. Occurrence of veterinary antibiotics in animal wastewater and surface water around farms in Jiangsu Province,China[J]. Chemosphere,2011,82(10):1408 − 1414. doi: 10.1016/j.chemosphere.2010.11.067

    CrossRef Google Scholar

    [19] ZHANG Qianqian,YING Guangguo,PAN Changgui,et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:Source analysis,multimedia modeling,and linkage to bacterial resistance[J]. Environmental Science & Technology,2015,49(11):6772 − 6782.

    Google Scholar

    [20] WATKINSON A J,MURBY E J,COSTANZO S D. Removal of antibiotics in conventional and advanced wastewater treatment:Implications for environmental discharge and wastewater recycling[J]. Water Research,2007,41(18):4164 − 4176. doi: 10.1016/j.watres.2007.04.005

    CrossRef Google Scholar

    [21] BALZER F,ZÜHLKE S,HANNAPPEL S. Antibiotics in groundwater under locations with high livestock density in Germany[J]. Water Science and Technology-Water Supply,2016,16(5):1361 − 1369. doi: 10.2166/ws.2016.050

    CrossRef Google Scholar

    [22] BURKE V,RICHTER D,GRESKOWIAK J,et al. Occurrence of antibiotics in surface and groundwater of a drinking water catchment area in Germany[J]. Water Environment Research,2016,88(7):652 − 659. doi: 10.2175/106143016X14609975746604

    CrossRef Google Scholar

    [23] SZEKERES E,CHIRIAC C M,BARICZ A,et al. Investigating antibiotics,antibiotic resistance genes,and microbial contaminants in groundwater in relation to the proximity of urban areas[J]. Environmental Pollution,2018,236:734 − 744. doi: 10.1016/j.envpol.2018.01.107

    CrossRef Google Scholar

    [24] ZAINAB S M,JUNAID M,XU N,et al. Antibiotics and antibiotic resistant genes (ARGs) in groundwater:A global review on dissemination,sources,interactions,environmental and human health risks[J]. Water Research,2020,187:116455. doi: 10.1016/j.watres.2020.116455

    CrossRef Google Scholar

    [25] 彭聪,巴俊杰,胡芬,等. 广西会仙岩溶湿地典型抗生素污染特征及生态风险评估[J]. 环境科学学报,2019,39(7):2207 − 2217. [PENG Cong,BA Junjie,HU Fen,et al. Typical antibiotic pollution characteristics and ecological risk assessment of Huixian Karst wetland in Guangxi,China[J]. Acta Scientiae Circumstantiae,2019,39(7):2207 − 2217. (in Chinese with English abstract)]

    Google Scholar

    PENG Cong, BA Junjie, HU Fen, et al. Typical antibiotic pollution characteristics and ecological risk assessment of Huixian Karst wetland in Guangxi, China[J]. Acta Scientiae Circumstantiae, 2019, 39（7）: 2207 − 2217. （in Chinese with English abstract）

    Google Scholar

    [26] QIN Litang,PANG Xinrui,ZENG Honghu,et al. Ecological and human health risk of sulfonamides in surface water and groundwater of Huixian Karst wetland in Guilin,China[J]. Science of the Total Environment,2020,708:134552. doi: 10.1016/j.scitotenv.2019.134552

    CrossRef Google Scholar

    [27] WANG Jialin,ZHANG Chong,XIONG Ling,et al. Changes of antibiotic occurrence and hydrochemistry in groundwater under the influence of the South-to-North Water Diversion (the Hutuo River,China)[J]. Science of the Total Environment,2022,832:154779. doi: 10.1016/j.scitotenv.2022.154779

    CrossRef Google Scholar

    [28] 黄福杨,单婷倩,林静,等. 典型西南岩溶地下水抗生素污染指示因子识别[J/OL]. 地质科技通报,(2023-02-24)[2023-11-03] [HUANG Fuyang,SHAN Tingqian,LIN Jing,et al. Identification of indicators for antibiotic pollution in typical karst groundwater, Southwest China[J]. Bulletin of Geological Science and Technology,(2023-02-24)[2023-11-03]. https://doi.org/10.19509/j.cnki.dzkq.tb20220466. (in Chinese with English abstract)]

    Google Scholar

    HUANG Fuyang, SHAN Tingqian, LIN Jing, et al. Identification of indicators for antibiotic pollution in typical karst groundwater, Southwest China[J]. Bulletin of Geological Science and Technology, （2023-02-24）[2023-11-03]. https://doi.org/10.19509/j.cnki.dzkq.tb20220466. （in Chinese with English abstract）

    Google Scholar

    [29] 赵兰坡,冯君,王宇,等. 松嫩平原盐碱地种稻开发的理论与技术问题[J]. 吉林农业大学学报,2012,34(3):237 − 241. [ZHAO Lanpo,FENG Jun,WANG Yu,et al. Theoretical and technological problems in the development of planting paddy in saline-alkali land of Songnen Plain[J]. Journal of Jilin Agricultural University,2012,34(3):237 − 241. (in Chinese with English abstract)]

    Google Scholar

    ZHAO Lanpo, FENG Jun, WANG Yu, et al. Theoretical and technological problems in the development of planting paddy in saline-alkali land of Songnen Plain[J]. Journal of Jilin Agricultural University, 2012, 34（3）: 237 − 241. （in Chinese with English abstract）

    Google Scholar

    [30] HUANG Fuyang,LI Zeyan,ZHANG Chong,et al. Pesticides in the typical agricultural groundwater in Songnen Plain,northeast China:Occurrence,spatial distribution and health risks[J]. Environmental Geochemistry and Health,2019,41(6):2681 − 2695. doi: 10.1007/s10653-019-00331-5

    CrossRef Google Scholar

    [31] FOSTER S,GARDUNO H,EVANS R,et al. Quaternary aquifer of the north China Plain:Assessing and achieving groundwater resource sustainability[J]. Hydrogeology Journal,2004,12(1):81 − 93. doi: 10.1007/s10040-003-0300-6

    CrossRef Google Scholar

    [32] LIU Changming,YU Jingjie,KENDY E. Groundwater exploitation and its impact on the environment in the North China Plain[J]. Water International,2001,26(2):265 − 272. doi: 10.1080/02508060108686913

    CrossRef Google Scholar

    [33] LU Yintao,TANG Changyuan,CHEN Jianyao,et al. Spatial characteristics of water quality,stable isotopes and tritium associated with groundwater flow in the Hutuo River alluvial fan plain of the North China Plain[J]. Hydrogeology Journal,2008,16(5):1003 − 1015. doi: 10.1007/s10040-008-0292-3

    CrossRef Google Scholar

    [34] LI Zhenwei,XU Xianli,LIU Meixian,et al. State-space prediction of spring discharge in a Karst catchment in southwest China[J]. Journal of Hydrology,2017,549:264 − 276. doi: 10.1016/j.jhydrol.2017.04.001

    CrossRef Google Scholar

    [35] XUE Qiang,QI Yinjie,LIU Fei. Ultra-high performance liquid chromatography-electrospray tandem mass spectrometry for the analysis of antibiotic residues in environmental waters[J]. Environmental Science and Pollution Research,2015,22(21):16857 − 16867. doi: 10.1007/s11356-015-4900-1

    CrossRef Google Scholar

    [36] LINDSEY M E,MEYER T M,THURMAN E M. Analysis of trace levels of sulfonamide and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography/mass spectrometry[J]. Analytical Chemistry,2001,73(19):4640 − 4646. doi: 10.1021/ac010514w

    CrossRef Google Scholar

    [37] SABRI N A,VAN HOLST S,SCHMITT H,et al. Fate of antibiotics and antibiotic resistance genes during conventional and additional treatment technologies in wastewater treatment plants[J]. Science of the Total Environment,2020,741:140199. doi: 10.1016/j.scitotenv.2020.140199

    CrossRef Google Scholar

    [38] ZOU Hua,HE Jiangtao,HE Baonan,et al. Sensitivity assessment of denitrifying bacteria against typical antibiotics in groundwater[J]. Environmental Science-Processes & Impacts,2019,21(9):1570 − 1579.

    Google Scholar

    [39] 张玉叶,何江涛,邓璐,等. 洛美沙星和诺氟沙星对水中生物反硝化过程的影响模拟试验[J]. 地学前缘,2022,29(5):497 − 507. [ZHANG Yuye,HE Jiangtao,DENG Lu,et al. Effects of lomefloxacin and norfloxacin on the biological water denitrification process:An experimental study[J]. Earth Science Frontiers,2022,29(5):497 − 507. (in Chinese with English abstract)]

    Google Scholar

    ZHANG Yuye, HE Jiangtao, DENG Lu, et al. Effects of lomefloxacin and norfloxacin on the biological water denitrification process: An experimental study[J]. Earth Science Frontiers, 2022, 29（5）: 497 − 507. （in Chinese with English abstract）

    Google Scholar

    [40] 邓璐,何江涛,邹华,等. 洛美沙星对水中反硝化过程的影响模拟试验[J]. 中国环境科学,2020,40(7):2934 − 2942. [DENG Lu,HE Jiangtao,ZOU Hua,et al. Simulation experiments on effects of lomefloxacin on denitrification process in water[J]. China Environmental Science,2020,40(7):2934 − 2942. ( in Chinese with English abstract)]

    Google Scholar

    DENG Lu, HE Jiangtao, ZOU Hua, et al. Simulation experiments on effects of lomefloxacin on denitrification process in water[J]. China Environmental Science, 2020, 40（7）: 2934 − 2942. （ in Chinese with English abstract）

    Google Scholar

    [41] FORD D,WILLIAMS P. Karst hydrogeology [M]. New Zealand:Karst Hydrogeology and Geomorphology,2007:103 − 144.

    Google Scholar

    [42] GOLDSCHEIDER N,DREW D. Methods in Karst hydrogeology [M]. London:Taylor & Francis,2007:264.

    Google Scholar

    [43] WORTHINGTON S R H,FORD D C. Self-organized permeability in carbonate aquifers[J]. Ground Water,2009,47(3):326 − 336. doi: 10.1111/j.1745-6584.2009.00551.x

    CrossRef Google Scholar

    [44] LOOS R,GAWLIK B M,LOCORO G,et al. EU-wide survey of polar organic persistent pollutants in European River waters[J]. Environmental Pollution,2009,157(2):

    Google Scholar

    [45] ZHOU Tian,HUANG Fuyang,ZHANG Chong,et al. Effects of hydrogeochemical conditions on the distribution of pesticides in the Karst River system[J]. Environmental Science and Pollution Research,2020,27(24):30468 − 30478. doi: 10.1007/s11356-020-09262-6

    CrossRef Google Scholar

    [46] BOY-ROURA M,MAS-PLA J,PETROVIC M,et al. Towards the understanding of antibiotic occurrence and transport in groundwater:Findings from the Baix Fluvià alluvial aquifer (NE Catalonia,Spain)[J]. Science of the Total Environment,2018,612:1387 − 1406. doi: 10.1016/j.scitotenv.2017.09.012

    CrossRef Google Scholar

    [47] MENCIÓ A,MAS-PLA J. Assessing the influence of environmental factors on groundwater antibiotic occurrence by means of variation partitioning[J]. Water,2019,11(7).

    Google Scholar

    [48] DZHAMALOV R G,ZLOBINA V L. Precipitation pollution effect on groundwater hydrochemical regime[J]. Environmental Geology,1995,25(1):65 − 68. doi: 10.1007/BF01061831

    CrossRef Google Scholar

    [49] YANG Qingchun,WANG Luchen,MA Hongyun,et al. Hydrochemical characterization and pollution sources identification of groundwater in Salawusu aquifer system of Ordos Basin,China[J]. Environmental Pollution,2016,216:340 − 349. doi: 10.1016/j.envpol.2016.05.076

    CrossRef Google Scholar

    [50] CARPENTER C M G,HELBLING D E. Widespread micropollutant monitoring in the Hudson River Estuary reveals spatiotemporal micropollutant clusters and their sources[J]. Environmental Science & Technology,2018,52(11):6187 − 6196.

    Google Scholar

    [51] GROS M,CATALÁN N,MAS-PLA J,et al. Groundwater antibiotic pollution and its relationship with dissolved organic matter:Identification and environmental implications[J]. Environmental Pollution,2021,289:117927. doi: 10.1016/j.envpol.2021.117927

    CrossRef Google Scholar

    [52] 王巧莲,蒋勇军,陈宇. 岩溶流域地下水 TOC 输出及影响因素分析:以重庆丰都雪玉洞地下河流域为例[J]. 环境科学,2016,37(5):1788 − 1797. [WANG Qiaolian,JIANG Yongjun,CHEN Yu. Export of total organic carbon (TOC) from Karst watershed and its influencing factors:An example from Xueyudong underground river system,Chongqing[J]. Environmental Science,2016,37(5):1788 − 1797. (in Chinese with English abstract)]

    Google Scholar

    WANG Qiaolian, JIANG Yongjun, CHEN Yu. Export of total organic carbon （TOC） from Karst watershed and its influencing factors: An example from Xueyudong underground river system, Chongqing[J]. Environmental Science, 2016, 37（5）: 1788 − 1797. （in Chinese with English abstract）

    Google Scholar

    [53] ZHI Dan,YANG Danxing,ZHENG Yongxin,et al. Current progress in the adsorption,transport and biodegradation of antibiotics in soil[J]. Journal of Environmental Management,2019,251:109598. doi: 10.1016/j.jenvman.2019.109598

    CrossRef Google Scholar

    [54] INGERSLEV F,TORÄNG L,LOKE M L,et al. Primary biodegradation of veterinary antibiotics in aerobic and anaerobic surface water simulation systems[J]. Chemosphere,2001,44(4):865 − 872. doi: 10.1016/S0045-6535(00)00479-3

    CrossRef Google Scholar

    • Relative Articles
  • Cited by
  • Supplements
    • Proportional views
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Figures(5)

Tables(1)

Export Citation
PDF
XML

Article Metrics

Article views(974) PDF downloads(92) Cited by(0)

Access History

Other Articles By Authors

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    版权所有：中国地质调查局发展研究中心 copyright @2020