Abstract: Lattice anchoring is one of the frequently used prevention technologies for slope and landslide engineering. A large-scale physical model test was adopted to explore the interaction of actual mechanics characteristics of lattice frame anchorage in the detritus soil slope. Using the compacted clay filling the indoor model experiment groove to simulate the landslide mass, and designing the lattice beams with the ratio of similitude 1:2.5, which revealed the whole deformation process in lattice beams of pre-stressed lattice anchorage system under the action of pre-stress, we monitored parameters of the soil pressure, stress of lattice and displacement of lattice. On the basis of analysis about stress-strain data and deformation signs, the following results are obtained:The deformation of the anchor points at the boundary of the lattice were more obvious than those of the interior, and also fractured nearby, in addition, the shape of deformed cross-beam was just like an arch bridge; The stress on each beam was near the inverted triangle distribution which was maximum at the beam crossing points; The stress distribution of the anchor points was linearly decreasing from the top to the bottom. The above research could provide some reference for engineering optimization design.