Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin

MA Jian-sheng; WANG Zhuo; ZHANG Ze-yu; LIU Qiang; LI Li-jun

doi:10.15898/j.cnki.11-2131/td.202101040001

2021 Vol. 40, No. 6

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MA Jian-sheng, WANG Zhuo, ZHANG Ze-yu, LIU Qiang, LI Li-jun. Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin[J]. Rock and Mineral Analysis, 2021, 40(6): 944-953. doi: 10.15898/j.cnki.11-2131/td.202101040001

Citation:

MA Jian-sheng, WANG Zhuo, ZHANG Ze-yu, LIU Qiang, LI Li-jun. Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin[J]. Rock and Mineral Analysis, 2021, 40(6): 944-953. doi: 10.15898/j.cnki.11-2131/td.202101040001

Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin

Shenyang Centre of Geological Survey, China Geological Survey, Shenyang 110032, China

More Information

Corresponding author: LI Li-jun, 475876904@qq.com

Received Date: 04 January 2021

Revised Date: 26 May 2021

Accepted Date: 28 July 2021

Publish Date: 28 November 2021

Abstract

Abstract

BACKGROUND
At present, the supervision of antibiotic abuse and its research is being strengthened. In recent years, antibiotics have been detected in varying degrees in water in central China. This reinforces the concern of the pollution of antibiotics in surface and groundwater.
OBJECTIVES
To investigate the distribution characteristics of 29 antibiotics in groundwater in Harbin.
METHODS
A total of 26 groups of groundwater samples were collected in Harbin, and the sampling scope included habitation and production areas such as densely populated, industrial production, agricultural districts and animal husbandry. The ultra-performance liquid chromatography-triple quadrupole mass spectrometry method was used to analyze 29 kinds of antibiotics covering six types, including sulfonamides, quinolones, macrolides, β-lactams, tetracyclines, and lincosamides.
RESULTS
Antibiotics in the groundwater of Harbin were mainly composed of sulfonamides, quinolones, macrolides and tetracyclines and the detection rates were 61.5%, 46.2%, 42.3% and 38.5%, respectively. The content of antibiotics detected ranged from 0.02 to 681ng/L, and the highest contents of sulfathiazole, sulfadiazine, and lincomycin were more than 100ng/L. The average content of quinolones was low compared with some domestic and international areas (such as Beijing, Tianjin, and Barcelona). Sampling sites with higher antibiotic levels were mainly found in the central, southern and eastern regions of the city. These areas are also relatively densely populated and are generally distributed around pharmaceutical factories, urban sewage outlets, and poultry and livestock farms.
CONCLUSIONS
The distribution characteristics of antibiotics in groundwater in Harbin are strongly related to the impact of human production and living activities.
- groundwater /
- antibiotics /
- quinolones /
- space distribution /
- ultra performance liquid chromatography-triple quadrupole mass spectrometry

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References

[1]	Li S, Shi W Z, You M T, et al. Antibiotics in water and sediments of Danjiangkou Reservoir, China: Spatiotemporal distribution and indicator screening[J]. Environmental Pollution, 2019, 246: 435-442. doi: 10.1016/j.envpol.2018.12.038 CrossRef Google Scholar
[2]	Liu L L, Wu W, Zhang J Y, et al. Progress of research on the toxicology of antibiotic pollution in aquatic organisms[J]. Acta Ecologica Sinica, 2018, 38: 36-41. doi: 10.1016/j.chnaes.2018.01.006 CrossRef Google Scholar
[3]	祁彦洁, 刘菲. 地下水中抗生素污染检测分析研究进展[J]. 岩矿测试, 2014, 33(1): 1-11. doi: 10.3969/j.issn.0254-5357.2014.01.002 CrossRef Google Scholar Qi Y J, Liu F. Analysis of antibiotics in groundwater: A review[J]. Rock and Mineral Analysis, 2014, 33(1): 1-11. doi: 10.3969/j.issn.0254-5357.2014.01.002 CrossRef Google Scholar
[4]	王路光, 朱晓磊, 王靖飞, 等. 环境水体中的残留抗生素及其潜在风险[J]. 工业水处理, 2009, 29(5): 11-14. Google Scholar Wang L G, Zhu X L, Wang J F, et al. Antibiotic residual in environmental water body and its potential risks[J]. Industrial Water Treatment, 2009, 29(5): 11-14. Google Scholar
[5]	Grgic I, Cizmek A M, Babic S, et al. UV filters as a driver of the antibiotic pollution in different water matrices[J]. Journal of Environmental Management, 2021, 289: 1-6. Google Scholar
[6]	Dickinson A W, Power A, Hansen M G, et al. Heavy metal pollution and co-selection for antibiotic resist-ance: A microbial palaeontology approach[J]. Environment International, 2019, 132: 1-10. Google Scholar
[7]	Barnes K K, Kolpin D W, Furlong E T, et al. A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States groundwater[J]. Science of the Total Environment, 2008, 402(2-3): 192-200. doi: 10.1016/j.scitotenv.2008.04.028 CrossRef Google Scholar
[8]	Hunt S B, Snow D D, Powell T D, et al. Occurrence of steroid hormones and antibiotics in shallow groundwater impacted by livestock waste control facilities[J]. Journal of Contaminant Hydrology, 2011, 123(3-4): 94-103. doi: 10.1016/j.jconhyd.2010.12.010 CrossRef Google Scholar
[9]	Serna R L, Jurado A, Suné E V, et al. Occurrence of 95 pharmaceuticals and transformation products in urban groundwaters underlying the metropolis of Barcelona, Spain[J]. Environmental Pollution, 2013, 174: 305-315. doi: 10.1016/j.envpol.2012.11.022 CrossRef Google Scholar
[10]	Sacher F, Lange F T, Brauch H J, et al. Pharmaceuticals in groundwaters analytical methods and results of a monitoring program in Baden-Wurttemberg, Germany[J]. Journal of Chromatography, 2001, 938(1-2): 199-210. doi: 10.1016/S0021-9673(01)01266-3 CrossRef Google Scholar
[11]	童蕾, 姚林林, 刘慧, 等. 抗生素在地下水系统中的环境行为及生态效应研究进展[J]. 生态毒理学报, 2016, 11(2): 27-36. Google Scholar Tong L, Yao L L, Liu H, et al. Review on the environmental behavior and ecological effect of antibiotics in groundwater system[J]. Asian Journal of Ecotoxicology, 2016, 11(2): 27-36. Google Scholar
[12]	Yi X Z, Lin C H, Ong E J L, et al. Occurrence and distribution of trace levels of antibiotics in surface waters and soils driven by non-point source pollution and anthropogenic pressure[J]. Chemosphere, 2019, 216: 213-223. doi: 10.1016/j.chemosphere.2018.10.087 CrossRef Google Scholar
[13]	赵富强, 高会, 张克玉, 等. 中国典型河流水域抗生素的赋存状况及风险评估研究[J]. 环境污染与防治, 2021, 43(1): 94-102. Google Scholar Zhao F Q, Gao H, Zhang K Y, et al. Occurrence and risk assessment of antibiotics in typical river basins in China[J]. Environmental Pollution and Control, 2021, 43(1): 94-102. Google Scholar
[14]	Yan C X, Yang Y, Zhou J L, et al. Antibiotics in the surface water of the Yangtze Estuary: Occurrence, distribution and risk assessment[J]. Environmental Pollution, 2013, 175: 22-29. doi: 10.1016/j.envpol.2012.12.008 CrossRef Google Scholar
[15]	秦延文, 张雷, 时瑶, 等. 大辽河表层水体典型抗生素污染特征与生态风险评价[J]. 环境科学研究, 2015, 28(3): 361-368. Google Scholar Qin Y W, Zhang L, Shi Y, et al. Contamination characteristics and ecological risk assessment of typical antibiotics in surface water of the Daliao River, China[J]. Research of Environmental Sciences, 2015, 28(3): 361-368. Google Scholar
[16]	杨常青, 王龙星, 侯晓虹, 等. 大辽河水系河水中16种抗生素的污染水平分析[J]. 色谱, 2012, 30(8): 756-762. Google Scholar Yang C Q, Wang L X, Hou X H, et al. Analysis of pollution level of 16 antibiotics in the river water of Daliao River water system[J]. Chinese Journal of Chromatography, 2012, 30(8): 756-762. Google Scholar
[17]	章强, 辛琦, 朱静敏, 等. 中国主要水域抗生素污染现状及其生态环境效应研究进展[J]. 环境化学, 2014, 33(7): 1075-1083. Google Scholar Zhang Q, Xin Q, Zhu J M, et al. The antibiotic contaminations in the main water bodies in China and the associated environmental and human health impacts[J]. Environmental Chemistry, 2014, 33(7): 1075-1083. Google Scholar
[18]	高立红, 史亚利, 厉文辉, 等. 抗生素环境行为及其环境效应研究进展[J]. 环境化学, 2013, 32(9): 1619-1633. Google Scholar Gao L H, Shi Y L, Li W H, et al. Environmental behavior and impacts of antibiotics[J]. Environmental Chemistry, 2013, 32(9): 1619-1633. Google Scholar
[19]	郭婕, 张燕, 胡振国, 等. 环境水样中农药污染分析技术研究进展[J]. 岩矿测试, 2021, 40(1): 16-32. Google Scholar Guo J, Zhang Y, Hu Z G, et al. A review of pesticide pollution analysis techniques for environ mental water samples[J]. Rock and Mineral Analysis, 2021, 40(1): 16-32. Google Scholar
[20]	徐蓉桢, 刘菲, 荆继红, 等. 典型浅层孔隙水和岩溶水中多环芳烃分布特征[J]. 岩矿测试, 2018, 37(4): 411-418. Google Scholar Xu R Z, Liu F, Jing J H, et al. Distribution characteristics of polycyclic aromatic hydrocarbons in typical shallow pore water and karst water[J]. Rock and Mineral Analysis, 2018, 37(4): 411-418. Google Scholar
[21]	朱帅, 沈亚婷, 贾静, 等. 环境介质中典型新型有机污染物分析技术研究进展[J]. 岩矿测试, 2018, 37(5): 586-606. Google Scholar Zhu S, Shen Y T, Jia J, et al. Review on the analytical methods of typical emerging organic pollutants in the environment[J]. Rock and Mineral Analysis, 2018, 37(5): 586-606. Google Scholar
[22]	陈卫平, 彭程伟, 杨阳, 等. 北京市地下水中典型抗生素分布特征与潜在风险[J]. 环境科学, 2017, 38(12): 5074-5080. Google Scholar Chen W P, Peng C W, Yang Y, et al. Distribution characteristics and risk analysis of antibiotic in the groundwater in Beijing[J]. Environmental Science, 2017, 38(12): 5074-5080. Google Scholar
[23]	Hu X G, Zhou Q X, Luo Y. Occurrence and source analy-sis of typical veterinary antibiotics in manure, soil vegetables and groundwater from organic vegetable base, northern China[J]. Enviromental Pollution, 2010, 158(9): 2992-2998. doi: 10.1016/j.envpol.2010.05.023 CrossRef Google Scholar
[24]	王伟华. 松花江流域哈尔滨段典型抗生素归趋及风险评价[D]. 哈尔滨: 东北林业大学, 2018: 37-65.http://cdmd.cnki.com.cn/Article/CDMD-10225-1018248374.htm Google Scholar Wang W H. The distribution, transformation and risk assessment of typical antibiotics in the Songhua River Basin of Harbin Secion[D]. Haerbin: Northeast Forestry University, 2018: 37-65. Google Scholar
[25]	郎朗, 董晓琪, 狄静波. SPE-HPLC法测定松花江哈尔滨段水样中11种抗生素[J]. 中国给水排水, 2018, 34(20): 114-118. Google Scholar Lang L, Dong X Q, Di J B. Determination of 11 antibiotics in Harbin Section of Songhua River by SPE-HPLC[J]. China Water & Wastewater, 2018, 34(20): 114-118. Google Scholar
[26]	李冶平, 邓昌州, 杨湘奎, 等. 哈尔滨市及周边地区第四系地下水水质综合评价[J]. 东北水利水电, 2014(1): 25-26, 55. doi: 10.3969/j.issn.1002-0624.2014.01.012 CrossRef Google Scholar Li Y P, Deng C Z, Yang X K, et al. Comprehensive assessment of Quaternary groundwater quality in Harbin City and the surrounding area[J]. Water Resources & Hydropower of Northeast, 2014(1): 25-26, 55. doi: 10.3969/j.issn.1002-0624.2014.01.012 CrossRef Google Scholar
[27]	杨亚妹. 哈尔滨市地下水流动系统特征分析[J]. 水利科技与经济, 2014, 20(1): 68-70. doi: 10.3969/j.issn.1006-7175.2014.01.029 CrossRef Google Scholar Yang Y M. The features analysis of flow system of groundwater in Haerbin[J]. Water Conservancy Science and Technology and Economy, 2014, 20(1): 68-70. doi: 10.3969/j.issn.1006-7175.2014.01.029 CrossRef Google Scholar
[28]	孔庆轩, 董宏志, 王燕, 等. 哈尔滨地区浅层地下水质量与污染评价[J]. 地质与资源, 2015, 24(1): 70-74. Google Scholar Kong Q X, Dong H Z, Wang Y, et al. Assessment for the quality and pollution of shallow groundwater in Harbin, Heilongjiang Province[J]. Geology and Resources, 2015, 24(1): 70-74. Google Scholar
[29]	徐晖, 吴明红, 徐刚. 高效液相色谱-串联质谱法对水环境中12种抗生素的检测[J]. 上海大学学报(自然科学版), 2017, 23(3): 483-490. Google Scholar Xu H, Wu M H, Xu G. Determination of 12 antibiotics in aqueous environment by high performance LC-MS/MS[J]. Journal of Shanghai University (Natural Science), 2017, 23(3): 483-490. Google Scholar
[30]	张金, 宗栋良, 常爱敏, 等. 水环境中典型抗生素SPE-UPLC-MS/MS检测方法的建立[J]. 环境化学, 2015, 34(8): 1446-1452. Google Scholar Zhang J, Zong D L, Chang A M, et al. Determination of common antibiotics in aquatic environment by solid-phase extraction and ultra pressure liquid chromatography tandem mass spectrometry (UPLC-MS/MS)[J]. Environmental Chemistry, 2015, 34(8): 1446-1452. Google Scholar
[31]	Tong L, Huang S B, Wang Y X, et al. Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China[J]. Science of The Total Environment, 2014, 497-498: 180-187. doi: 10.1016/j.scitotenv.2014.07.068 CrossRef Google Scholar
[32]	Chen L, Lang H, Liu F, et al. Presence of antibiotics in shallow groundwater in the northern and southwestern regions of China[J]. Groundwater, 2018, 56(3): 451-457. doi: 10.1111/gwat.12596 CrossRef Google Scholar
[33]	郭东赫, 蔺宝钢. 水体中的抗生素污染[J]. 生态经济, 2020, 36(7): 5-8. Google Scholar Guo D H, Lin B G. Antibiotic pollution in water[J]. Ecological Economy, 2020, 36(7): 5-8. Google Scholar
[34]	刘昔, 王智, 王学雷, 等. 我国典型区域地表水环境中抗生素污染现状及其生态风险评价[J]. 环境科学, 2019, 40(5): 2094-2100. Google Scholar Liu X, Wang Z, Wang X L, et al. Status of antibiotic contamination and ecological risks assessment of several typical Chinese surface-water environments[J]. Environmental Science, 2019, 40(5): 2094-2100. Google Scholar